Pharmacist
Scientific interests:
Experimental analytics of endocannabinoids and other lipids
Academic education:
1998-2004 Study of Pharmacy, Rheinische Friedrich-Wilhelms-University Bonn
2008-2015 Postgraduate student at the University of Cologne
Doctoral thesis:
2015 Dr. rer. medic. (rerum medicinalium) / Doctor of Biomedicine: „Exploration of endocannabinoids and related fatty acide ethanolamides in serum of patients suffering Borderline Personlty Disorders and/or Posttraumatic Stress Disorders: Validation of a LC-MS/MS method.“, University of Cologne, Germany
Professional experience:
2006-2009 Postgraduate researcher, Dept. of Psychiaty and Psychotherapy, University of Cologne, Research group Experimental and Clinical Neuropsychopharmacology
2006-2012 Pharmacist at the German Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte) (part time)
2009-2015 Postgraduate researcher, Dept. of Psychiaty and Psychotherapy, Central Institute of Mental Health, Mannheim, RG Translational Research in Psychiatry
2016 Post doc, Dept. of Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim
2016-2018 Project Manager, Centre for Clinical Trials, Bonn University
2021-current Project Manager, Endosane Pharmaceuticals GmbH, Berlin
Publications:
- T. A. Couttas, C. Boost, F. Pahlisch, E. B. Sykorova, D. Koethe, J. E. Leweke, H. Endepols, C. Rohleder, F. M. Leweke (2022) Simultaneous assessment of serum levels and pharmacologic effects of cannabinoids on endocannabinoids and N-acylethanolamines by liquid chromatography – tandem mass spectrometry. Cannabis Cannabinoid Res (in press)
- Y. Bouter, M. M. Brzózka, R. Rygula, C. Boost, F. M. Leweke, U. Havemann-Reinecke*, C. Rohleder* (2019) Chronic psychosocial stress causes increased anxiety-like behavior and alters endocannabinoid levels in the brain in C57Bl/6J mice. Cannabis Cannabinoid Res 5:51-61
- M. Schneider, F. Kasanetz, D. L. Lynch, C. M. Friemel, O. Lasalle, D. P. Hurst, F. Steindel, K. Monory, C. Schaefer, I. Miederer, F. M. Leweke, M. Schreckenberger, B. Lutz, P. H. Reggio, O. J. Manzoni, R. Spanagel (2015) Enhanced functional activity of the cannabinoid type-1 receptor mediate adolescent behavior. J Neurosci 31: 13975–88
- M. Grosshans, E. Schwarz, J. M. Bumb, C. Schaefer, C. Rohleder, C. Vollmert, S. Vollstadt-Klein, H. Tost, A. Meyer-Lindenberg, F. Kiefer, F. M. Leweke (2014) Oleoylethanolamide and human neural responses to food stimuli in obesity. JAMA Psychiatry 71, 1254-61.
- C. Schaefer, F. Enning, J. K. Mueller, J. M. Bumb, C. Rohleder, T. M. Odorfer, J. Klosterkotter, M. Hellmich, D. Koethe, C. Schmahl, M. Bohus, F. M. Leweke (2014) Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. Eur Arch Psychiatry Clin Neurosci 264:459-463.
- C. J. Morgan, E. Page, C. Schaefer, K. Chatten, A. Manocha, S. Gulati, H. V. Curran, B. Brandner, F. M. Leweke (2013) Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. Br J Psychiatry 202:381-382